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All answers having "Shackle" as clue:

4 Character Answers:

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DRIP

GYVE

IRON

YOKE



5 Character Answers:

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CHAIN



6 Character Answers:

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FETTER

HOGTIE

PINION



7 Character Answers:

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ENCHAIN

ENSLAVE

LEGIRON

MANACLE



8 Character Answers:

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HANDCUFF