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All answers having "Irritates" as clue:

4 Character Answers:

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BUMS

IRES

IRKS

NAGS



5 Character Answers:

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GALLS

GNAWS

MIFFS

RASPS

RILES

ROILS

VEXES



6 Character Answers:

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ANNOYS

CHAFES

EATSAT

GETSTO

GRATES

ITCHES

PEEVES

PIQUES

SMARTS

TEASES



7 Character Answers:

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ABRADES

FESTERS

JANGLES

NETTLES

RANKLES

RUFFLES



8 Character Answers:

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GRATESON

TICKSOFF



15 Character Answers:

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DRIVESUPTHEWALL

RATTLESONESCAGE

RUBSTHEWRONGWAY