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All answers having "Insignificant one" as clue:

4 Character Answers:

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SNIP

TWIT



5 Character Answers:

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SPRAT

TWERP



6 Character Answers:

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NOBODY

PEANUT

SQUIRT



8 Character Answers:

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HALFPINT



9 Character Answers:

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PIPSQUEAK



12 Character Answers:

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LITTLESHRIMP