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All answers having "Columbus" as clue:

3 Character Answers:

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AVE

CIR



5 Character Answers:

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CHRIS



6 Character Answers:

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EPONYM

GENOAN

MADMAN

SCIOTO



7 Character Answers:

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GENOESE

MARINER



8 Character Answers:

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GENOVESE

SEAFARER



10 Character Answers:

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SANTAMARIA



13 Character Answers:

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CAPITALOFOHIO



14 Character Answers:

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MIDWESTCAPITAL

OCTOBERHONOREE



15 Character Answers:

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CIRCLEINNEWYORK

CITYNEARATLANTA