To kill, murder. Example: Our foes must all be slain.
To eradicate or stamp out. Example: You must slay these thoughts.
(by extension) To defeat, overcome (in a competition or contest). Example: 1956, “Giants Slay Bears in Pro Title Battle”, in Lodi News-Sentinel, 1956 December 31, page 8.
To delight or overwhelm, especially with laughter. Example: Ha ha! You slay me!
To amaze, stun or otherwise incapacitate by awesomeness; to be awesome at something; to kill (slang sense).
To have sex with
All clues having "SLAY"
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You can find a list of possible crossword clues for SLAY below.